Sugi Predict

Sugi Predict / Compounds / SCHEMBL10025577

SCHEMBL10025577

SCHEMBL10025577

CCN(CCO)c1ccc(N=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.51
▸ MAPT P10636 8/20 0.51
▸ NPC1 O15118 2/20 0.51
▸ RAB9A P51151 2/20 0.51
▸ PSMD14 O00487 2/20 0.51
▸ MITF O75030 1/20 0.51
▸ KDM4E B2RXH2 8/20 0.48
▸ MEN1 O00255 8/20 0.48
▸ GAA P10253 6/20 0.48
▸ TDP1 Q9NUW8 3/20 0.48
▸ ALDH1A1 P00352 12/20 0.47
▸ MAPK1 P28482 4/20 0.47
▸ TSHR P16473 3/20 0.47
▸ TP53 P04637 1/20 0.47
▸ HIF1A Q16665 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ LMNA P02545 3/20 0.42
▸ CRHBP P24387 1/20 0.42
▸ CRHR2 Q13324 1/20 0.42
▸ ALDH3A1 P30838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17847422 0.98 KMT2A (0.50) KMT2AMAPTNPC1RAB9APSMD14
SCHEMBL13452275 0.95 KMT2A (0.58) KMT2AMAPTNPC1RAB9APSMD14
SCHEMBL147073 0.89 ALDH1A1 (0.48) KMT2AMAPTNPC1RAB9APSMD14
Hydrochloric Acid SCHEMBL6254389 0.87 ALDH1A1 (0.47) KMT2AMAPTNPC1RAB9APSMD14
SCHEMBL25485940 0.85 KMT2A (0.65) KMT2AMAPTNPC1RAB9APSMD14
SCHEMBL11914176 0.85 ALDH1A1 (0.43) KMT2AMAPTNPC1RAB9APSMD14
SCHEMBL146443 0.85 ALDH1A1 (0.58) KMT2AMAPTNPC1RAB9APSMD14
SCHEMBL8038944 0.84 ALDH1A1 (0.50) KMT2AMAPTNPC1RAB9APSMD14
Hydrochloric Acid SCHEMBL11586430 0.83 ALDH1A1 (0.56) KMT2AMAPTNPC1RAB9APSMD14
Hydrochloric Acid SCHEMBL8040784 0.82 KMT2A (0.49) KMT2AMAPTNPC1RAB9APSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108818-B Particles for electrophoretic displays 默克专利股份有限公司 2021-01-01 — — CN disclosed
US-10435566-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-08 — — US disclosed
EP-3233944-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-09-04 — — EP disclosed
EP-2791250-B1 PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF OREAL (FR) 2019-04-03 — — EP disclosed
EP-2791250-B1 PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF OREAL (FR) 2019-04-03 — — EP disclosed
US-20180037744-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2018-02-08 — — US disclosed
EP-3233944-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2017-10-25 — — EP disclosed
WO-2016096091-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2016-06-23 — — WO disclosed
US-9226883-B2 Particular azomethine direct dyes, dye composition comprising at least one such compound, implementation process therefore and use thereof L'OREAL (FR) 2016-01-05 — — US disclosed
US-9226883-B2 Particular azomethine direct dyes, dye composition comprising at least one such compound, implementation process therefore and use thereof L'OREAL (FR) 2016-01-05 — — US disclosed
WO-2013087636-A1 PARTICULAR AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH COMPOUND, IMPLEMENTATION PROCESS THEREFORE AND USE THEREOF L'OREAL (FR) 2013-06-20 — — WO disclosed
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-08-09 — — US disclosed
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-08-09 — — US disclosed
US-20120193029-A1 COMPOSITIONS FOR POLYMER BONDING LOCTITE (R&D) LIMITED (IE) 2012-08-02 — — US disclosed
US-20120193029-A1 COMPOSITIONS FOR POLYMER BONDING LOCTITE (R&D) LIMITED (IE) 2012-08-02 — — US disclosed
US-20120164904-A1 BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-06-28 — — US disclosed
US-20120164904-A1 BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2012-06-28 — — US disclosed
WO-2011032998-A1 PHOSPHONATE BONDING COMPOSITIONS LOCTITE (R&D) LIMITED (IE) 2011-03-24 — — WO disclosed
US-4675355-A REACTIVE AMINE-CONTAINING NITROSO COMPOUND AND AN HALOGENATED ALKYLBENZENE TO IMPROVE GREEN STRENGTH; TIRES BRIDGESTONE CORPORATION (JP) 1987-06-23 — — US disclosed
US-3970423-A PHENYLENEDIAMINE DERIVATIVES CLAIROL INCORPORATED (US) 1976-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120164904-A1 BONDING COMPOSITIONS AOX1, NOXO1, RIOX2 KMT2A 1264/4885MAPT 4518/4885NPC1 4880/4885
US-20180037744-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, GYPA, SELP KMT2A 4104/4885MAPT 2891/4885NPC1 2992/4885
US-10435566-B2 Particles for electrophoretic displays RAB5IF, SELP, SELE KMT2A 4291/4885MAPT 3084/4885NPC1 2952/4885
US-20120202091-A1 PHOSPHONATE BONDING COMPOSITIONS NOXO1, DDO, PTK2 KMT2A 1652/4885MAPT 2053/4885NPC1 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.