Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.57 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | CASP1 | P29466 | 4/20 | 0.53 |
| ▸ | CASP7 | P55210 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23563365 | 0.87 | MEN1 (0.57) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL13256237 | 0.78 | CDK5 (0.57) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL4024272 | 0.76 | CDK5 (0.68) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL9450612 | 0.76 | CDK5 (0.72) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL11174222 | 0.76 | CDK5 (0.59) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL22549691 | 0.76 | CDK5 (0.55) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL9078891 | 0.75 | CDK5 (0.67) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL14712322 | 0.75 | KDM4E (0.58) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL9450624 | 0.75 | KDM4E (0.73) | CDK5CDK5R1KDM4EALDH1A1HPGD | |
| SCHEMBL9450643 | 0.75 | CDK5 (0.55) | CDK5CDK5R1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130045952-A1 | ABA Receptor Agonists for Increased Plant Stress Resistance | VAN ANDEL RESEARCH INSTITUTE (US) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045952-A1 | ABA Receptor Agonists for Increased Plant Stress Resistance | BROX, AAK1, ADORA3 | CDK5 2316/4885CDK5R1 1196/4885KDM4E 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.