Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 10/20 | 0.47 |
| ▸ | NMT2 | O60551 | 9/20 | 0.47 |
| ▸ | CD40 | P25942 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 3/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20272636 | 0.95 | NMT1 (0.46) | NMT1NMT2CD40GNAI3GNAO1 | |
| SCHEMBL14576026 | 0.95 | NMT1 (0.46) | NMT1NMT2CD40GNAI3GNAO1 | |
| SCHEMBL20706554 | 0.94 | NMT1 (0.48) | NMT1NMT2CD40GNAI3GNAO1 | |
| SCHEMBL18359086 | 0.94 | GNAI3 (0.47) | NMT1NMT2CD40GNAI3GNAO1 | |
| SCHEMBL14642615 | 0.90 | GNAI3 (0.44) | NMT1NMT2CD40GNAI3GNAO1 | |
| SCHEMBL14642614 | 0.90 | GNAI3 (0.49) | NMT1NMT2GNAI3GNAO1GNAI1 | |
| SCHEMBL15084741 | 0.89 | NMT1 (0.42) | NMT1NMT2CD40GNAI3GNAO1 | |
| SCHEMBL21233587 | 0.87 | NMT1 (0.43) | NMT1NMT2CD40GNAI3GNAO1 | |
| SCHEMBL18653794 | 0.85 | GNAI3 (0.55) | CD40GNAI3GNAO1GNAI1CHRNA1 | |
| SCHEMBL14916812 | 0.85 | GNAI3 (0.55) | CD40GNAI3GNAO1GNAI1CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170952-A9 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2013-02-21 | — | — | WO | disclosed |