SCHEMBL14916812

SCHEMBL14916812

NCCCCC(N)C(=O)NCCCOCCOCCOCCCNC(=O)CCOCCOCCOCCOCCOCCC(=O)NCCCOCCOCCOCCCNC(=O)C(N)CCCCN

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GNAI3 P08754 1/20 0.55
▸ GNAO1 P09471 1/20 0.55
▸ GNAI1 P63096 1/20 0.55
▸ TLR2 O60603 4/20 0.46
▸ TERT O14746 5/20 0.45
▸ DPP7 Q9UHL4 2/20 0.44
▸ RRM1 P23921 1/20 0.43
▸ CD40 P25942 1/20 0.43
▸ CA2 P00918 1/20 0.42
▸ NOS1 P29475 1/20 0.40
▸ MMP2 P08253 1/20 0.40
▸ GSR P00390 1/20 0.39
▸ CHRNA1 P02708 2/20 0.39
▸ CHRNG P07510 2/20 0.39
▸ CHRNB1 P11230 2/20 0.39
▸ CHRND Q07001 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18653794 1.00 GNAI3 (0.55) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14239755 1.00 GNAI3 (0.55) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL20272608 0.99 GNAI3 (0.57) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL20706553 0.99 GNAI3 (0.57) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14240716 0.96 GNAI3 (0.51) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14240586 0.95 GNAI3 (0.50) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616413 0.94 GNAI3 (0.59) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616462 0.94 GNAI3 (0.59) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616485 0.94 GNAI3 (0.52) GNAI3GNAO1GNAI1TLR2TERT
SCHEMBL14616412 0.94 GNAI3 (0.52) GNAI3GNAO1GNAI1TLR2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3673898-A1 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY Nitto Denko Corporation (JP) 2020-07-01 — — EP claimed
EP-2773326-B1 METHOD FOR STERILELY PRODUCING LIPID-NUCLEIC ACID PARTICLES NITTO DENKO CORP (JP) 2019-02-20 — — EP claimed
US-10155945-B2 Method of producing lipid nanoparticles for drug delivery NITTO DENKO CORPORATION (JP) 2018-12-18 — — US claimed
US-20170152516-A1 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY NITTO DENKO CORPORATION (JP) 2017-06-01 — — US claimed
EP-3673898-A1 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY Nitto Denko Corporation (JP) 2020-07-01 — — EP disclosed
EP-3485875-A1 SINGLE USE SYSTEM FOR STERELILY PRODUCING LIPID-NUCLEIC ACID PARTICLES Nitto Denko Corporation (JP) 2019-05-22 — — EP disclosed
EP-2773326-B1 METHOD FOR STERILELY PRODUCING LIPID-NUCLEIC ACID PARTICLES NITTO DENKO CORP (JP) 2019-02-20 — — EP disclosed
US-10155945-B2 Method of producing lipid nanoparticles for drug delivery NITTO DENKO CORPORATION (JP) 2018-12-18 — — US disclosed
US-20170152516-A1 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY NITTO DENKO CORPORATION (JP) 2017-06-01 — — US disclosed
US-9579338-B2 Method of producing lipid nanoparticles for drug delivery NITTO DENKO CORPORATION (JP) 2017-02-28 — — US disclosed
US-8956572-B2 Single use system for sterilely producing lipid-nucleic acid particles NITTO DENKO CORPORATION (JP) 2015-02-17 — — US disclosed
US-20130164400-A1 SINGLE USE SYSTEM FOR STERILELY PRODUCING LIPID-NUCLEIC ACID PARTICLES NITTO DENKO CORPORATION (JP) 2013-06-27 — — US disclosed
US-20130115274-A1 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY NITTO DENKO CORPORATION (JP) 2013-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130164400-A1 SINGLE USE SYSTEM FOR STERILELY PRODUCING LIPID-NUCLEIC ACID PARTICLES RNGTT, SPOUT1, NASP GNAI3 2686/4885GNAO1 3998/4885GNAI1 2963/4885
US-20130115274-A1 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY PHOSPHO1, LIPA, LIPC GNAI3 2110/4885GNAO1 3930/4885GNAI1 2316/4885
US-20170152516-A1 METHOD OF PRODUCING LIPID NANOPARTICLES FOR DRUG DELIVERY PHOSPHO1, LIPA, LIPC GNAI3 2110/4885GNAO1 3930/4885GNAI1 2316/4885
US-10155945-B2 Method of producing lipid nanoparticles for drug delivery PHOSPHO1, LIPA, LIPC GNAI3 2110/4885GNAO1 3930/4885GNAI1 2316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback