Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 11/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304336 | 0.92 | CYP1A1 (0.45) | CYP1A1LMNASMN1; SMN2ALDH1A1F2 | |
| SCHEMBL14217380 | 0.87 | CYP1A1 (0.42) | CYP1A1LMNASMN1; SMN2ALDH1A1F2 | |
| SCHEMBL14217346 | 0.87 | F2 (0.43) | CYP1A1LMNASMN1; SMN2ALDH1A1F2 | |
| SCHEMBL14217369 | 0.86 | CYP1A1 (0.53) | CYP1A1LMNASMN1; SMN2ALDH1A1F2 | |
| SCHEMBL12353905 | 0.83 | ALDH1A1 (0.51) | CYP1A1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14217340 | 0.83 | F2 (0.44) | CYP1A1LMNASMN1; SMN2ALDH1A1F2 | |
| SCHEMBL2304867 | 0.83 | CYP1A1 (0.44) | CYP1A1LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2303056 | 0.83 | LMNA (0.56) | CYP1A1LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2235106 | 0.83 | LMNA (0.56) | CYP1A1LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2302728 | 0.82 | CYP1A1 (0.58) | CYP1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013023274-A1 | SUBSTITUTED 2-IMIDAZOLIDINONES AND 2-IMIDAZOLONES AND THEIR USE IN THE TREATMENT OF CANCER | UNIVERSITE LAVAL (CA) | 2013-02-21 | — | — | WO | disclosed |