Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306201 | 0.76 | L3MBTL1 (0.42) | L3MBTL1CSNK2A1PIM3CLK4HCAR2 | |
| SCHEMBL29790182 | 0.75 | L3MBTL1 (0.38) | L3MBTL1CSNK2A1PIM3CLK4ALDH1A1 | |
| SCHEMBL3567804 | 0.72 | ALDH1A1 (0.38) | L3MBTL1CSNK2A1PIM3CLK4RAB9A | |
| SCHEMBL8188239 | 0.71 | KDM4E (0.40) | L3MBTL1CSNK2A1PIM3CLK4ALDH1A1 | |
| SCHEMBL8307577 | 0.71 | ALDH1A1 (0.39) | L3MBTL1CSNK2A1PIM3CLK4HCAR2 | |
| SCHEMBL9956341 | 0.71 | L3MBTL1 (0.38) | L3MBTL1CSNK2A1PIM3CLK4HCAR2 | |
| SCHEMBL3574484 | 0.68 | L3MBTL1 (0.46) | L3MBTL1CSNK2A1PIM3CLK4RAB9A | |
| SCHEMBL16571689 | 0.68 | HCAR2 (0.35) | L3MBTL1HCAR2 | |
| SCHEMBL3404681 | 0.65 | ALDH1A1 (0.44) | L3MBTL1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL20027633 | 0.64 | HPGD (0.44) | RAB9AALDH1A1KDM4EKMT2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |