Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14709101 | 0.87 | CA1 (0.42) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL2034947 | 0.85 | LIPG (0.39) | LPLLIPGHIF1ACA1CA2 | |
| SCHEMBL14709228 | 0.83 | SMN1; SMN2 (0.37) | HIF1ACA1CA2CA9DGAT1 | |
| SCHEMBL14709417 | 0.83 | LIPG (0.49) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL14712080 | 0.82 | CA1 (0.41) | LPLLIPGHIF1ACA1CA2 | |
| SCHEMBL14711235 | 0.82 | HRH3 (0.43) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL14711627 | 0.81 | HRH3 (0.42) | LPLLIPGHIF1ACA1CA2 | |
| SCHEMBL14790408 | 0.80 | HIF1A (0.36) | LPLLIPGHIF1ACA1CA2 | |
| SCHEMBL15912438 | 0.80 | ALDH1A1 (0.41) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL14712137 | 0.79 | AAK1 (0.38) | LPLLIPGHIF1ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |