SCHEMBL1471068

SCHEMBL1471068

COc1ccccc1N(c1ccccc1)c1ccccc1/C=C/c1cc(C#N)c(/C=C/c2ccccc2N(c2ccccc2)c2ccccc2OC)cc1C#N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 1/20 0.40
SLC16A1 P53985 1/20 0.40
NFE2L2 Q16236 4/20 0.40
TRPA1 O75762 1/20 0.40
IMPDH2 P12268 1/20 0.39
IMPDH1 P20839 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.38
CYP1A1 P04798 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP1B1 Q16678 2/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
CYP19A1 P11511 1/20 0.37
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11888684 0.89 AR (0.38) SLC16A3SLC16A1NFE2L2TRPA1IMPDH2
SCHEMBL7075585 0.88 NFE2L2 (0.44) SLC16A3SLC16A1NFE2L2TRPA1IMPDH2
SCHEMBL7075586 0.88 NFE2L2 (0.44) SLC16A3SLC16A1NFE2L2TRPA1IMPDH2
SCHEMBL5862343 0.78 NFE2L2 (0.40) SLC16A3SLC16A1NFE2L2TRPA1IMPDH2
SCHEMBL5862346 0.78 NFE2L2 (0.40) SLC16A3SLC16A1NFE2L2TRPA1IMPDH2
SCHEMBL20386672 0.77 CA1 (0.50) NFE2L2TRPA1SMN1; SMN2NPC1RAB9A
SCHEMBL4669496 0.73 CA1 (0.50) NFE2L2TRPA1SMN1; SMN2NPC1RAB9A
SCHEMBL29449742 0.73 CA1 (0.50) NFE2L2TRPA1SMN1; SMN2NPC1RAB9A
SCHEMBL18327869 0.73 TRPA1 (0.51) SLC16A3SLC16A1NFE2L2TRPA1CYP1A1
SCHEMBL830304 0.73 TRPA1 (0.51) SLC16A3SLC16A1NFE2L2TRPA1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8786185-B2 Organic electroluminescence display device SONY CORPORATION (JP) 2014-07-22 US disclosed
US-20140124772-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE SONY CORPORATION (JP) 2014-05-08 US disclosed
US-8680761-B2 Organic electroluminescence display device including wiring and stacked structure SONY CORPORATION (JP) 2014-03-25 US disclosed
US-20130175517-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE SONY CORPORATION (JP) 2013-07-11 US disclosed
US-8436530-B2 Organic electroluminescence display device SONY CORPORATION (JP) 2013-05-07 US disclosed
US-7915816-B2 Organic electroluminescence display device comprising auxiliary wiring SONY CORPORATION (JP) 2011-03-29 US disclosed
US-20080284323-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE SONY CORPORATION (JP) 2008-11-20 US disclosed