SCHEMBL1471088

SCHEMBL1471088

CCCCCCC(=O)O[SiH3]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.61
LMNA P02545 2/20 0.57
PAM P19021 2/20 0.55
CES2 O00748 3/20 0.54
CES1 P23141 3/20 0.54
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
GPR84 Q9NQS5 6/20 0.52
PPARG P37231 6/20 0.52
PPARD Q03181 6/20 0.52
PPARA Q07869 6/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
PTPN1 P18031 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27946615 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL7103487 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL27940024 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL7119586 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL992131 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL1980440 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL8893194 1.00 DGKA (0.61) DGKALMNAPAMCES2CES1
SCHEMBL4408942 0.98 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL10898814 0.98 DGKA (0.59) DGKALMNAPAMCES2CES1
SCHEMBL721169 0.98 DGKA (0.59) DGKALMNAPAMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP claimed
EP-2699606-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP Bridgestone Corporation (JP) 2014-02-26 EP claimed
EP-2483317-B1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2014-02-26 EP claimed
US-20140018500-A1 Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group BRIDGESTONE CORPORATION (JP) 2014-01-16 US claimed
WO-2012135451-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-10-04 WO claimed
CN-102639568-A Functionalized polymers and methods for their manufacture BRIDGESTONE CORP 2012-08-15 CN claimed
EP-2483317-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-08-08 EP claimed
US-20120184677-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2012-07-19 US claimed
WO-2011041534-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-04-07 WO claimed
US-20110077325-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-03-31 US claimed
US-7915181-B2 Repair and restoration of damaged dielectric materials and films HONEYWELL INTERNATIONAL INC. (US) 2011-03-29 US claimed
US-6518205-B1 Multifunctional reagents for the surface modification of nanoporous silica films ALLIEDSIGNAL INC. 2003-02-11 US claimed
US-6208014-B1 HYDROPHOBIC DIELECTRIC FILM PRODUCED BY REACTING A HYDROPHILIC SILICA FILM WITH A MULTIFUNCTIONAL SURFACE MODIFICATION AGENT THAT IS CAPABLE OF SILYLATING OR CAPPING SILANOL MOIETIES ON HYDROPHILIC SURFACES ALLIEDSIGNAL, INC. 2001-03-27 US claimed
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP disclosed
US-9403919-B2 Polymers functionalized with a carboxylic or thiocarboxylic ester containing a silylated amino group BRIDGESTONE CORPORATION (JP) 2016-08-02 US disclosed
EP-1292973-B1 METHOD TO RESTORE HYDROPHOBICITY IN DIELECTRIC FILMS AND MATERIALS HONEYWELL INT INC (US) 2015-09-09 EP disclosed
WO-2001018860-A2 IMPROVED APPARATUS AND METHODS FOR INTEGRATED CIRCUIT PLANARIZATION ALLIEDSIGNAL INC. (US) 2001-03-15 WO disclosed
WO-2001015214-A1 NANOPOROUS SILICA TREATED WITH SILOXANE POLYMERS FOR ULSI APPLICATIONS ALLIEDSIGNAL INC. (US) 2001-03-01 WO disclosed
WO-2000044036-A1 USE OF MULTIFUNCTIONAL SI-BASED OLIGOMER/POLYMER FOR THE SURFACE MODIFICATION OF NANOPOROUS SILICA FILMS ALLIEDSIGNAL INC. (US) 2000-07-27 WO disclosed
WO-2000002233-A2 SIMPLIFIED PROCESS FOR PRODUCING NANOPOROUS SILICA ALLIEDSIGNAL INC. (US) 2000-01-13 WO disclosed