Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946615 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL27940024 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL7119586 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL992131 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL1980440 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL8893194 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL1471088 | 1.00 | DGKA (0.61) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL4408942 | 0.98 | DGKA (0.59) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL10898814 | 0.98 | DGKA (0.59) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL721169 | 0.98 | DGKA (0.59) | DGKALMNAPAMCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127886-B1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | HOFFMANN LA ROCHE (CH) | 2003-05-07 | — | — | EP | claimed |
| US-6552204-B1 | Lactonization of an acyl halide and a ketene acetal or reacting acyl halide with malonate half acid then cyclizing; high yield | ROCHE COLORADO CORPORATION | 2003-04-22 | — | — | US | claimed |
| EP-1127886-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-29 | — | — | EP | claimed |
| CN-115305089-B | Cadmium-containing quantum dot and preparation method and application thereof | 纳晶科技股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115305089-A | Cadmium-containing quantum dot and preparation method and application thereof | 纳晶科技股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-102149759-A | New catalysts for the cross-linking of functional silanes or functional siloxanes, particularly with substrates | EVONIK DEGUSSA GMBH | 2011-08-10 | — | — | CN | disclosed |
| EP-1127886-B1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | HOFFMANN LA ROCHE (CH) | 2003-05-07 | — | — | EP | disclosed |
| EP-1127886-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-29 | — | — | EP | disclosed |