Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.61 |
| ▸ | NPBWR1 | P48145 | 9/20 | 0.56 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15245160 | 0.87 | DGAT1 (0.79) | DGAT1KCNH2NPBWR1SOAT1PDPK1 | |
| SCHEMBL15245140 | 0.85 | DGAT1 (0.67) | DGAT1KCNH2NPBWR1SOAT1 | |
| SCHEMBL29091542 | 0.84 | NPBWR1 (0.78) | DGAT1KCNH2NPBWR1SOAT1PDPK1 | |
| SCHEMBL30615051 | 0.84 | NPBWR1 (0.78) | DGAT1KCNH2NPBWR1SOAT1PDPK1 | |
| SCHEMBL22955338 | 0.83 | CYP3A4 (0.55) | DGAT1KCNH2NPBWR1PDPK1KDM4E | |
| SCHEMBL15245240 | 0.82 | DGAT1 (0.65) | DGAT1KCNH2NPBWR1SOAT1PDPK1 | |
| SCHEMBL2361397 | 0.82 | DGAT1 (0.51) | DGAT1KCNH2NPBWR1SOAT1 | |
| SCHEMBL15245227 | 0.80 | HDAC6 (0.62) | DGAT1KCNH2NPBWR1SOAT1 | |
| SCHEMBL15245149 | 0.80 | DGAT1 (0.80) | DGAT1KCNH2NPBWR1SOAT1MAPK1 | |
| SCHEMBL15245159 | 0.80 | DGAT1 (0.84) | DGAT1KCNH2NPBWR1SOAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |