SCHEMBL1471137

SCHEMBL1471137

C[Si](C)(C)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.55
GAA P10253 2/20 0.52
MAPT P10636 1/20 0.52
ALDH1A1 P00352 2/20 0.50
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.45
ELANE P08246 1/20 0.45
ATM Q13315 3/20 0.44
CDC25B P30305 1/20 0.44
MAPK14 Q16539 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
SRD5A2 P31213 1/20 0.43
HSP90AA1 P07900 1/20 0.43
PKM P14618 1/20 0.43
CCR6 P51684 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TLR9 Q9NR96 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30464698 1.00 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL20510174 0.87 ALDH1A1 (0.45) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL20510176 0.85 AKR1C3 (0.48) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL106081 0.81 ALDH1A1 (0.56) AKR1C3MAPTALDH1A1SMN1; SMN2TDP1
SCHEMBL13714163 0.80 ALDH1A1 (0.61) GAAMAPTALDH1A1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL9411948 0.79 ALDH1A1 (0.54) AKR1C3MAPTALDH1A1SMN1; SMN2TDP1
SCHEMBL29447165 0.78 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL700595 0.78 AKR1C3 (0.85) AKR1C3GAAMAPTALDH1A1KMT2A
SCHEMBL8861756 0.77 MAPK1 (0.42) MAPTALDH1A1KMT2AMEN1SMN1; SMN2
SCHEMBL7738430 0.76 GAA (0.55) GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115851125-B Double-component silicone rubber anti-pollution flashover coating for insulation protection of power system and preparation method and application thereof 国网山东省电力公司电力科学研究院 2023-12-08 CN claimed
CN-115851125-A Double-component silicone rubber anti-pollution flashover coating for insulation protection of power system and preparation method and application thereof 国网山东省电力公司电力科学研究院 2023-03-28 CN claimed
CN-115851125-B Double-component silicone rubber anti-pollution flashover coating for insulation protection of power system and preparation method and application thereof 国网山东省电力公司电力科学研究院 2023-12-08 CN disclosed
CN-115851125-A Double-component silicone rubber anti-pollution flashover coating for insulation protection of power system and preparation method and application thereof 国网山东省电力公司电力科学研究院 2023-03-28 CN disclosed
CN-110650990-B Fluorescent porous organic nanosheets for chemical sensing 新加坡国立大学 2022-12-20 CN disclosed
CN-110650990-A Fluorescent porous organic nanosheets for chemical sensing 新加坡国立大学 2020-01-03 CN disclosed
US-7939600-B2 Binder for electric double layer capacitor electrode ZEON CORPORATION (JP) 2011-05-10 US disclosed
US-7915378-B2 Material for solid polymer electrolyte, and polyether polymer and process for producing same NISHIO HIDEYUKI 2011-03-29 US disclosed
US-7482092-B2 Polymer battery having the outer peripheries of the separator and negative electrode positioned outside of an outer periphery of the positive electrode SHARP KABUSHIKI KAISHA (JP) 2009-01-27 US disclosed
EP-1507268-B1 MATERIAL FOR SOLID POLYMER ELECTROLYTE, AND POLYETHER POLYMER AND PROCESS FOR PRODUCING SAME ZEON CORP (JP) 2008-12-03 EP disclosed
US-20080044731-A1 Material for solid polymer electrolyte, and polyether polymer and process for producing same NISHIO HIDEYUKI 2008-02-21 US disclosed
US-5436090-A Crosslinked tri-functional acrylic acid-modified polyethylene glycol solid electrolyte DAI-ICHI KOGYO SEIGAKU CO., LTD. (JP) 1995-07-25 US disclosed
EP-0537930-B1 Solid electrolyte DAI ICHI KOGYO SEIYAKU CO LTD (JP) 1995-05-24 EP disclosed
US-5356553-A Solvent and electrolyte salt dissolved in trifunctional terminal acryloyl modified alkylene oxide polyether DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1994-10-18 US disclosed
EP-0596148-A1 Electrically conductive polymer composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1994-05-11 EP disclosed
EP-0581296-A2 Ionically conductive organosiloxane polymer compositions Dow Corning Toray Silicone Co., Ltd. (JP) 1994-02-02 EP disclosed
EP-0576686-A1 CELL DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1994-01-05 EP disclosed
EP-0537930-A1 Solid electrolyte DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1993-04-21 EP disclosed
US-4908283-A Curing acryloyl-denatured polyalkylene oxide and inorganic ion salt by irradiating with active rays UBE INDUSTRIES, LTD. (JP) 1990-03-13 US disclosed
US-4179295-A VINYL POLYSILOXANES, MERCAPTO POLYSILOXANES SHIN-ETSU CHEMICAL CO. LTD. (JP) 1979-12-18 US disclosed