SCHEMBL7738430

SCHEMBL7738430

CNC(=O)c1ccccc1[Si](C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.55
PLK1 P53350 2/20 0.52
KAT2B Q92831 1/20 0.44
BAZ2B Q9UIF8 1/20 0.44
BRD4 O60885 5/20 0.42
BRD2 P25440 1/20 0.41
BRD3 Q15059 1/20 0.41
BRDT Q58F21 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
POLB P06746 1/20 0.41
ADRA1D P25100 1/20 0.40
ADRA1A P35348 1/20 0.40
ADRA1B P35368 1/20 0.40
MAPK10 P53779 1/20 0.39
PDK2 Q15119 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8078737 0.82 POLB (0.38) GAAPLK1POLB
SCHEMBL2344909 0.80 GAA (0.71) GAAPLK1KAT2BBAZ2BBRD4
SCHEMBL7219605 0.79 L3MBTL1 (0.49) BRD4ADRA1DADRA1AADRA1B
SCHEMBL20510174 0.79 ALDH1A1 (0.45) GAASLC6A2ADRA1A
SCHEMBL16828923 0.78 POLB (0.35) GAAPOLB
SCHEMBL11519985 0.78 KEAP1 (0.51) GAAPOLB
SCHEMBL8861756 0.77 MAPK1 (0.42) BRD4POLB
SCHEMBL106081 0.77 ALDH1A1 (0.56) POLB
SCHEMBL1471137 0.76 AKR1C3 (0.55) GAAPOLB
SCHEMBL30464698 0.76 AKR1C3 (0.55) GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100415750-C Fungicides for the control of take-all disease of plants MONSANTO CO (US) 2008-09-03 CN disclosed
CN-1239495-C Bactericide for preventing and treating plant take-all disease MONSANTO CO (US) 2006-02-01 CN disclosed
CN-1636457-A Fungicides for the control of take-all disease of plants MONSANTO CO (US) 2005-07-13 CN disclosed
CN-1188420-C Fungicides for control of take-all disease of plants MONSANTO CO (US) 2005-02-09 CN disclosed
CN-1188419-C Bactericide for preventing and treating plant take-all disease MONSANTO CO (US) 2005-02-09 CN disclosed
US-6410558-B1 USING INDOLE OR QUINOLINE COMPOUND MONSANTO TECHNOLOGY LLC 2002-06-25 US disclosed
US-6248894-B1 SUBSTITUTED PYRROLES MONSANTO COMPANY 2001-06-19 US disclosed
US-6166057-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 2000-12-26 US disclosed
US-6133252-A THIOPHENE AND N-BONDED HETEROCYCLIC COMPOUND CHOSEN FROM THE GROUP CONSISTING OF MORPHOLINE, PIPERAZINE, PIPERIDINE, AND PYRROLIDINE, EACH OPTIONALLY SUBSTITUTED WITH C1-C6 ALKYL GROUPS MONSANTO COMPANY (US) 2000-10-17 US disclosed
US-6028101-A Fungicides for the control of take-all disease of plants MONSANTO COMPANY (US) 2000-02-22 US disclosed
US-5998466-A PREPLANTING MONSANTO COMPANY (US) 1999-12-07 US disclosed
CN-1225365-A Fungicides for control of take-all disease of plants MONSANTO CO (US) 1999-08-11 CN disclosed
CN-1225364-A Fungicides for control of take-all disease of plants MONSANTO CO (US) 1999-08-11 CN disclosed
CN-1221746-A Bactericide for preventing and treating plant take-all disease MONSANTO CO (US) 1999-07-07 CN disclosed
CN-1221745-A Bactericide for preventing and treating plant take-all disease MONSANTO CO (US) 1999-07-07 CN disclosed
CN-1043835-C Bactericide for preventing and treating plant take-all disease MONSANTO CO (US) 1999-06-30 CN disclosed
CN-1085221-A Bactericide for preventing and treating plant take-all disease MONSANTO CO (US) 1994-04-13 CN disclosed