Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 1.00 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | STAT6 | P42226 | 1/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20626176 | 1.00 | ADORA3 (1.00) | ADORA3SLC29A1TP53TDP1PAX8 | |
| SCHEMBL14713272 | 1.00 | ADORA3 (1.00) | ADORA3SLC29A1TP53TDP1PAX8 | |
| SCHEMBL20626177 | 1.00 | ADORA3 (1.00) | ADORA3SLC29A1TP53TDP1PAX8 | |
| SCHEMBL27429961 | 0.91 | ADORA3 (0.83) | ADORA3SLC29A1TP53TDP1LMNA | |
| SCHEMBL6760931 | 0.91 | ADORA3 (0.83) | ADORA3SLC29A1TP53TDP1LMNA | |
| SCHEMBL19991754 | 0.87 | ADORA3 (0.77) | ADORA3SLC29A1TP53TDP1PAX8 | |
| SCHEMBL1797170 | 0.87 | ADORA3 (0.76) | ADORA3SLC29A1TP53TDP1PAX8 | |
| SCHEMBL1795974 | 0.86 | ADORA3 (0.75) | ADORA3SLC29A1TP53TDP1PAX8 | |
| SCHEMBL1797185 | 0.86 | ADORA3 (0.75) | ADORA3SLC29A1TP53TDP1PAX8 | |
| SCHEMBL30519261 | 0.86 | ADORA3 (0.75) | ADORA3SLC29A1TP53TDP1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264613-A1 | COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN | ACADEMIA SINICA (TW) | 2016-09-15 | — | — | US | disclosed |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2013-02-21 | — | — | US | disclosed |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264613-A1 | COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN | ADORA2A, ADORA3, ADORA2B | ADORA3 2/4885SLC29A1 340/4885TP53 2705/4885 |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | ADORA2A, ADORA3, ADORA1 | ADORA3 2/4885SLC29A1 267/4885TP53 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.