Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 16/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471748 | 0.91 | FAAH (0.58) | FAAH | |
| SCHEMBL1471464 | 0.90 | FAAH (0.59) | FAAHCES1 | |
| SCHEMBL1471721 | 0.90 | FAAH (0.58) | FAAHCES1 | |
| SCHEMBL1471371 | 0.87 | FAAH (0.47) | FAAHCES1 | |
| SCHEMBL1471589 | 0.86 | FAAH (0.49) | FAAHCES1 | |
| SCHEMBL1472087 | 0.86 | FAAH (0.55) | FAAH | |
| SCHEMBL1472056 | 0.86 | FAAH (0.54) | FAAHCES1 | |
| SCHEMBL1471729 | 0.85 | FAAH (0.53) | FAAHCES1 | |
| SCHEMBL1471925 | 0.84 | FAAH (0.52) | FAAHCES1 | |
| SCHEMBL1471896 | 0.84 | FAAH (0.54) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1983994-B1 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2015-09-30 | — | — | EP | disclosed |
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | disclosed |
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885KDM4E 277/4885NPC1 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.