SCHEMBL1471409

SCHEMBL1471409

C[Si](C)(C)COCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1822519 0.78
SCHEMBL1470657 0.75
SCHEMBL6057337 0.72
SCHEMBL845123 0.69
SCHEMBL5579 0.69
SCHEMBL6852459 0.68 ALDH1A1 (0.36)
SCHEMBL736944 0.67
Hydrochloric Acid SCHEMBL1958678 0.67
SCHEMBL514355 0.67
Hydrochloric Acid SCHEMBL866238 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038462-A2 INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2025-02-20 WO disclosed
US-11376241-B2 Aryl hydrocarbon receptor (AhR) modulator compounds PHENEX PHARMACEUTICALS AG (DE) 2022-07-05 US disclosed
CN-110248940-B Aryl hydrocarbon receptor (AhR) modulator compounds 菲尼克斯药品股份公司 2022-07-01 CN disclosed
US-20220089597-A1 COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2 NOVARTIS AG (CH) 2022-03-24 US disclosed
US-20210309663-A1 COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2 NOVARTIS AG (CH) 2021-10-07 US disclosed
US-10981908-B2 Aryl hydrocarbon receptor (AHR) modulator compounds PHENEX PHARMACEUTICALS AG (DE) 2021-04-20 US disclosed
US-10975080-B2 Compounds and compositions for inhibiting the activity of SHP2 NOVARTIS AG (CH) 2021-04-13 US disclosed
EP-3577112-B1 ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS PHENEX PHARMACEUTICALS AG (DE) 2020-12-30 EP disclosed
EP-3577115-B1 ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS PHENEX PHARMACEUTICALS AG (DE) 2020-12-02 EP disclosed
US-20190185475-A1 COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2 NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2019-06-20 US disclosed
WO-2018141857-A1 ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS PHENEX PHARMACEUTICALS AG (DE) 2018-08-09 WO disclosed
EP-3310779-A1 COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2 Novartis AG (CH) 2018-04-25 EP disclosed
WO-2016203404-A1 COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2 NOVARTIS AG (CH) 2016-12-22 WO disclosed
EP-1799694-B1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE DOW CORNING TORAY CO LTD (JP) 2012-05-09 EP disclosed
US-7915439-B2 Method of producing silylalkoxymethyl halide DOW CORNING TORAY COMPANY, LTD. (JP) 2011-03-29 US disclosed
US-7679884-B2 Organosilicon phosphorus-based electrolytes WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-03-16 US disclosed
US-20100029970-A1 Organosilicon Phosphorus-Based Electrolytes WISCONSIN ALUMNI RESEARCH FOUNDATION 2010-02-04 US disclosed
US-20090203932-A1 Method of Producing Silylalkoxymethyl Halide DOW CORNING TORAY CO., LTD. (JP) 2009-08-13 US disclosed
EP-1799694-A1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE Dow Corning Toray Co., Ltd. (JP) 2007-06-27 EP disclosed
WO-2006040964-A1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE DOW CORNING TORAY CO., LTD. (JP) 2006-04-20 WO disclosed