⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714865 | 0.88 | — | — | |
| SCHEMBL14714351 | 0.77 | — | — | |
| SCHEMBL14714665 | 0.76 | DPP4 (0.33) | — | |
| SCHEMBL30007451 | 0.70 | — | — | |
| SCHEMBL14714686 | 0.66 | HSD11B1 (0.30) | — | |
| SCHEMBL23043416 | 0.64 | — | — | |
| SCHEMBL19549708 | 0.61 | — | — | |
| SCHEMBL22443592 | 0.61 | APLNR (0.32) | — | |
| SCHEMBL19897217 | 0.59 | FFAR3 (0.33) | — | |
| SCHEMBL9978302 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2747764-B1 | STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND USE OF SAME | FORSCHUNGSVERBUND BERLIN EV (DE) | 2017-05-03 | — | — | EP | disclosed |
| US-9242985-B2 | Structural mimetics of proline-rich peptides and use thereof | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2016-01-26 | — | — | US | disclosed |
| EP-2561873-A1 | Structural mimetics of proline-rich peptides and use of same | Forschungsverbund Berlin e.V. (DE) | 2013-02-27 | — | — | EP | disclosed |