SCHEMBL14714845

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14715049	0.87	PPARG (0.51)	HRH3PPARGMMP1ANPEPMMP2
	SCHEMBL14715425	0.86	PPARG (0.50)	HRH3PPARGMMP1MEN1KMT2A
	SCHEMBL14714764	0.86	HRH3 (0.49)	HRH3PPARGMMP1ANPEPMMP2
	SCHEMBL14715327	0.85	ALDH1A1 (0.50)	HRH3PPARGANPEP
	SCHEMBL14714987	0.85	HRH3 (0.45)	HRH3PPARGMMP1ANPEPMMP2
	SCHEMBL14714981	0.85	ANPEP (0.49)	HRH3PPARGMMP1ANPEPMMP2
	SCHEMBL14714895	0.84	PPARG (0.46)	HRH3PPARGMMP1MEN1KMT2A
	SCHEMBL14714497	0.84	PPARG (0.51)	HRH3PPARGMMP1ANPEPTAS1R3
	SCHEMBL14714735	0.83	PPARG (0.49)	HRH3PPARGANPEP
	SCHEMBL14714713	0.83	USP2 (0.46)	HRH3PPARGMMP1ANPEPMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.