SCHEMBL14714916

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7291468	0.96	HRH3 (0.92)	HRH3HRH1HRH2MAPK1ALDH1A1
	SCHEMBL8795398	0.92	HRH3 (0.84)	HRH3HRH1HRH2MAPK1ALDH1A1
	SCHEMBL14393458	0.90	HRH3 (0.88)	HRH3HRH1HRH2
	Hydrochloric Acid SCHEMBL1714618	0.88	HRH3 (0.86)	HRH3HRH1HRH2
	SCHEMBL424774	0.88	HRH3 (0.79)	HRH3HRH1HRH2MAPK1ALDH1A1
	SCHEMBL6922135	0.87	HRH3 (1.00)	HRH3HRH1HRH2KCNH2
	SCHEMBL27914448	0.86	HRH3 (0.76)	HRH3HRH1HRH2MAPK1ALDH1A1
	SCHEMBL1715391	0.85	HRH3 (0.84)	HRH3HRH1HRH2
	SCHEMBL3141155	0.84	HRH3 (0.73)	HRH3HRH1HRH2MAPK1ALDH1A1
	SCHEMBL4090612	0.84	HRH3 (0.82)	HRH3HRH1HRH2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.