Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715289 | 0.78 | NPC1 (0.37) | TYK2RAB9ANPC1 | |
| SCHEMBL10758301 | 0.78 | KDM4E (0.56) | RAB9ANPC1KDM4EGAAMAPT | |
| SCHEMBL3368022 | 0.75 | TYK2 (0.70) | TYK2RAB9ANPC1NAPRTCFTR | |
| SCHEMBL114359 | 0.75 | TYK2 (0.65) | TYK2RAB9ANPC1NAPRTIKBKE | |
| SCHEMBL150787 | 0.72 | BCAT2 (0.53) | TYK2RAB9ANPC1KDM4E | |
| SCHEMBL1161155 | 0.72 | TYK2 (0.69) | TYK2RAB9ANPC1NAPRTKDM4E | |
| SCHEMBL6916843 | 0.71 | NAPRT (0.62) | TYK2RAB9ANPC1NAPRTSMYD3 | |
| Hydrochloric Acid SCHEMBL2591261 | 0.71 | TYK2 (0.68) | TYK2RAB9ANPC1NAPRTKDM4E | |
| SCHEMBL21938137 | 0.71 | TYK2 (0.68) | TYK2RAB9ANPC1NAPRTCFTR | |
| SCHEMBL1663526 | 0.70 | NAPRT (0.60) | TYK2RAB9ANPC1NAPRTSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562174-A1 | Herbicidal 6-Oxo-1,6-dihydropyrimidin-5-carboxamides and 2-Oxo-1,2-dihydropyridin-3-carboxamides | Bayer Cropscience AG (DE) | 2013-02-27 | — | — | EP | disclosed |