SCHEMBL150787

SCHEMBL150787

O=C(Nc1cnn[nH]1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 3/20 0.53
KCNQ3 O43525 1/20 0.51
KCNQ2 O43526 1/20 0.51
JAK2 O60674 2/20 0.50
NAMPT P43490 2/20 0.50
TYK2 P29597 1/20 0.50
NPC1 O15118 4/20 0.49
RAB9A P51151 4/20 0.49
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49
PTPN1 P18031 1/20 0.49
P4HTM Q9NXG6 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SIRT1 Q96EB6 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
CCNA2 P20248 1/20 0.46
CDK2 P24941 1/20 0.46
CCNA1 P78396 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14958536 0.84 LMNA (0.62) NAMPTNPC1RAB9AKCNK3MEN1
SCHEMBL10758301 0.79 KDM4E (0.56) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL13411808 0.76 ALDH1A1 (0.46) RAB9AMEN1KMT2AKDM4EPOLB
SCHEMBL13715556 0.74 MEN1 (0.58) NPC1RAB9AMEN1KMT2A
SCHEMBL4760376 0.74 SIRT2 (0.62) BCAT2JAK2NAMPTTYK2NPC1
SCHEMBL7672965 0.74 RAB9A (0.60) JAK2NAMPTTYK2NPC1RAB9A
SCHEMBL5020210 0.73 KCNK3 (0.58) JAK2NPC1RAB9AKCNK3KCNK9
SCHEMBL14715007 0.72 TYK2 (0.53) TYK2NPC1RAB9AKDM4E
SCHEMBL31590676 0.71 KCNQ3 (0.54) KCNQ3KCNQ2JAK2NPC1RAB9A
SCHEMBL17283670 0.71 CCNA2 (0.69) NPC1RAB9AMEN1KMT2ACCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025103939-A1 SULFONIMIDOYL BENZAMIDES WITH HERBICIDAL ACTION BAYER AKTIENGESELLSCHAFT (DE) 2025-05-22 WO disclosed
CN-117616016-A Chiral 3-sulfinyl benzoic acid 拜耳公司 2024-02-27 CN disclosed
CN-114340610-A Multivalent fibroblast targeting agents and methods of use 普渡研究基金会 2022-04-12 CN disclosed
US-20200369629-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2020-11-26 US disclosed
EP-3737670-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2020-11-18 EP disclosed
US-20200331866-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2020-10-22 US disclosed
EP-3717460-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2020-10-07 EP disclosed
US-10653674-B2 Multisubstituted aromatic compounds as inhibitors of thrombin VERSEON CORPORATION (US) 2020-05-19 US disclosed
WO-2019162308-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2019-08-29 WO disclosed
WO-2019162309-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2019-08-29 WO disclosed
WO-2013064457-A1 5-PHENYL-SUBSTITUTED N-(TETRAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES AND N-(TRIAZOL-5-YL) ARYL CARBOXYLIC ACID AMIDES, AND USE THEREOF AS HERBICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-05-10 WO disclosed
EP-2589598-A1 5-phenyl substituted N-(Tetrazol-5-yl)- and N-(Triazol-5-yl)aryl carboxylic acid amides and use of same as herbicides Bayer CropScience AG (DE) 2013-05-08 EP disclosed
US-20130040950-A1 MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN VERSEON CORPORATION (US) 2013-02-14 US disclosed
WO-2013017559-A1 N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-02-07 WO disclosed
WO-2012123409-A1 N-(1,2,5-OXADIAZOL-3-YL)-, N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)BICYCLOARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2012-09-20 WO disclosed
US-20120058892-A1 N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (US) 2012-03-08 US disclosed
WO-2012028579-A1 N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND USE THEREOF AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2012-03-08 WO disclosed
WO-2011126903-A2 MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN VERSEON, INC. (US) 2011-10-13 WO disclosed
US-20090203215-A1 METAL POLISHING SLURRY AND CHEMICAL MECHANICAL POLISHING METHOD FUJIFILM CORPORATION (JP) 2009-08-13 US disclosed
US-20090203215-A1 METAL POLISHING SLURRY AND CHEMICAL MECHANICAL POLISHING METHOD FUJIFILM CORPORATION (JP) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120058892-A1 N-(TETRAZOL-5-YL)- AND N-(TRIAZOL-5-YL)ARYLCARBOXAMIDES AND THEIR USE AS HERBICIDES ZYX, NAT1, CYCS BCAT2 860/4885KCNQ3 1068/4885KCNQ2 1083/4885
US-10653674-B2 Multisubstituted aromatic compounds as inhibitors of thrombin TFPI, PLAT, SERPINC1 BCAT2 942/4885KCNQ3 2363/4885KCNQ2 2367/4885
US-20200369629-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES CBR3, CBR1, BBC3 BCAT2 211/4885KCNQ3 171/4885KCNQ2 488/4885
US-20130040950-A1 MULTISUBSTITUTED AROMATIC COMPOUNDS AS INHIBITORS OF THROMBIN TFPI, PLAT, SERPINC1 BCAT2 942/4885KCNQ3 2363/4885KCNQ2 2367/4885
US-20200331866-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES DDT, NIT2, BBOX1 BCAT2 83/4885KCNQ3 1306/4885KCNQ2 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.