Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.39 |
| ▸ | CASP1 | P29466 | 6/20 | 0.39 |
| ▸ | CASP7 | P55210 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715164 | 0.87 | HSD17B10 (0.40) | AOC3POLBHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL14973719 | 0.75 | GAA (0.43) | POLBALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL14973632 | 0.70 | L3MBTL1 (0.51) | POLBALDH1A1CYP1A2MAPK1TP53 | |
| SCHEMBL14715116 | 0.70 | ALDH1A1 (0.45) | POLBALDH1A1CYP1A2HPGDTP53 | |
| SCHEMBL14974309 | 0.69 | GAA (0.44) | POLBALDH1A1CYP1A2HPGDMEN1 | |
| SCHEMBL14974220 | 0.69 | ALDH1A1 (0.57) | HSD17B10ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL14982903 | 0.68 | ALDH1A1 (0.39) | AOC3POLBHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL14974605 | 0.68 | ALDH1A1 (0.45) | POLBALDH1A1CYP1A2HPGDMEN1 | |
| SCHEMBL14973980 | 0.68 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL14715161 | 0.68 | GAA (0.39) | POLBALDH1A1CYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | claimed |
| EP-2562157-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | Peking University (CN) | 2013-02-27 | — | — | EP | claimed |
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
| EP-2562157-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | Peking University (CN) | 2013-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | LTK, ERBB2, ABL1 | AOC3 3454/4885POLB 2417/4885HSD17B10 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.