SCHEMBL14715387

SCHEMBL14715387

CCCCNc1nc(N)nc(N(CCO)CCCC)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 11/20 0.60
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
HSP90AA1 P07900 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
CASP3 P42574 1/20 0.44
HTT P42858 1/20 0.44
CDK9 P50750 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
TLR8 Q9NR97 5/20 0.41
TLR7 Q9NYK1 3/20 0.41
CRHR1 P34998 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2370354 0.93 SLC29A1 (0.49) SLC29A1KMT2AKDM4EMEN1NPC1
SCHEMBL3301414 0.86 SLC29A1 (0.51) SLC29A1KMT2AMEN1LMNAMAPT
SCHEMBL11293174 0.85 SLC29A1 (0.49) SLC29A1KMT2AKDM4EMEN1NPC1
SCHEMBL25434244 0.85 SLC29A1 (0.49) SLC29A1KMT2AKDM4EMEN1NPC1
SCHEMBL1077004 0.84 SLC29A1 (0.46) SLC29A1KMT2AKDM4EMEN1ALDH1A1
SCHEMBL2838653 0.84 SLC29A1 (0.54) SLC29A1KMT2AKDM4EMEN1ALDH1A1
SCHEMBL2784212 0.83 ALDH1A1 (0.46) SLC29A1KMT2AKDM4EMEN1NPC1
SCHEMBL6641031 0.82 SLC29A1 (0.51) SLC29A1KMT2ASMN1; SMN2CRHR1
SCHEMBL6720244 0.82 SLC29A1 (0.51) SLC29A1KMT2AMAPTSMN1; SMN2CRHR1
SCHEMBL4289077 0.82 ALDH1A1 (0.42) SLC29A1KMT2AKDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2562864-A1 Proton-conducting polymer Nippon Steel Chemical Co., Ltd. (JP) 2013-02-27 EP disclosed