SCHEMBL1077004

SCHEMBL1077004

Nc1nc(NCCO)nc(N(CCO)CCO)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 19/20 0.46
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
PDE2A O00408 1/20 0.40
RGS12 O14924 1/20 0.40
SLC22A2 O15244 1/20 0.40
SLC22A1 O15245 1/20 0.40
ABCC4 O15439 1/20 0.40
ABCC5 O15440 1/20 0.40
PDE6D O43924 1/20 0.40
PDE8A O60658 1/20 0.40
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
PDE5A O76074 1/20 0.40
ABCB11 O95342 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
HSP90AA1 P07900 1/20 0.40
CHRM2 P08172 1/20 0.40
ABCB1 P08183 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3301414 0.93 SLC29A1 (0.51) SLC29A1MEN1LMNAGAAMAPT
SCHEMBL2219150 0.88 SLC29A1 (0.49) SLC29A1MEN1GAAKMT2A
SCHEMBL1032559 0.88 SLC29A1 (0.49) SLC29A1MEN1GAAKMT2A
SCHEMBL14715387 0.84 SLC29A1 (0.60) SLC29A1KDM4EMEN1ALDH1A1LMNA
SCHEMBL14159189 0.81 SLC29A1 (0.46) SLC29A1KDM4EMEN1PDE2ARGS12
SCHEMBL10454781 0.80 CA1 (0.38) SLC29A1KDM4EMEN1ALDH1A1LMNA
SCHEMBL2834273 0.80 SLC29A1 (0.53) SLC29A1KDM4EMEN1PDE2ARGS12
SCHEMBL1031350 0.80 KMT2A (0.50) SLC29A1MEN1GAACYP2D6CYP2C19
SCHEMBL1033545 0.80 KMT2A (0.50) SLC29A1KDM4EMEN1ALDH1A1GAA
SCHEMBL1032941 0.80 SLC29A1 (0.53) SLC29A1KDM4EMEN1PDE2ARGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010066686-A2 NOVEL TRIAZINE POLYMERS, METHOD FOR THE PRODUCTION AND USE THEREOF BOREALIS AGROLINZ MELAMINE GMBH (AT) 2010-06-17 WO claimed
EP-0390278-A1 3-(1,3-oxazolidinyl)-s-triazine DSM N.V. (NL) 1990-10-03 EP claimed
EP-2268610-B1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP BOREALIS AGROLINZ MELAMINE (AT) 2016-08-03 EP disclosed
US-8871842-B2 Method for producing a compound with at least one at least monosubstituted amino group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2014-10-28 US disclosed
EP-2774922-A1 Method for obtaining a functionalized triazine compound and the triazine compound obtained by said method Borealis Agrolinz Melamine GmbH (AT) 2014-09-10 EP disclosed
US-20110178212-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group BOREALIS AGROLINZ MELAMINE GMBH (AT) 2011-07-21 US disclosed
EP-2268610-A1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP Borealis Agrolinz Melamine GmbH (AT) 2011-01-05 EP disclosed
WO-2010066686-A2 NOVEL TRIAZINE POLYMERS, METHOD FOR THE PRODUCTION AND USE THEREOF BOREALIS AGROLINZ MELAMINE GMBH (AT) 2010-06-17 WO disclosed
WO-2009121603-A1 METHOD FOR PRODUCING A COMPOUND WITH AT LEAST ONE AT LEAST MONOSUBSTITUTED AMINO GROUP BOREALIS AGROLINZ MELAMINE GMBH (AT) 2009-10-08 WO disclosed
US-20040054083-A1 Coating with volatile-free aminoplast crosslinker BASF CORPORATION (US) 2004-03-18 US disclosed
WO-2001044333-A1 THERMOSETTING RESIN OBTAINED BY REACTION OF A TRIAZINE COMPOUND WITH AN ALDEHYDE AND AN ACTIVATED OLEFINIC COMPOUND DSM N.V. (NL) 2001-06-21 WO disclosed
US-5536795-A ADHESIVES AND PAINTS AND FIREPROOFING THERMOSETTING RESINS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-16 US disclosed
US-5480947-A N-METHYLOL DIGUANAMINES MITSUI TOATSU CHEMICALS, INC. (JP) 1996-01-02 US disclosed
EP-0612797-A2 Modification method of resins MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-08-31 EP disclosed
EP-0390278-A1 3-(1,3-oxazolidinyl)-s-triazine DSM N.V. (NL) 1990-10-03 EP disclosed
EP-0166297-B1 PROCESS FOR THE PREPARATION OF (2-HYDROXYETHYL)MELAMINES BASF Aktiengesellschaft (DE) 1988-08-31 EP disclosed
EP-0225433-A2 Hydroxyoxaalkyl melamines, process for their preparation and their use BASF Aktiengesellschaft (DE) 1987-06-16 EP disclosed
US-4668785-A FROM MELAMINE AND ETHANOLAMINE, ACID CATALYST BASF AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed
EP-0221330-A1 Foams and fibres made of melamine resins having an increased rigidity BASF Aktiengesellschaft (DE) 1987-05-13 EP disclosed
EP-0166297-A1 Process for the preparation of (2-hydroxyethyl)melamines BASF Aktiengesellschaft (DE) 1986-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178212-A1 Method for Producing a Compound with at Least One at Least Monosubstituted Amino Group INMT, AADAT, AANAT SLC29A1 1070/4885KDM4E 1856/4885MEN1 380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.