Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL14715701 | 0.90 | MAPT (0.47) | MAPTALDH1A1LMNAMEN1KMT2A | |
| Carbamic Acid SCHEMBL14715641 | 0.90 | MAPT (0.47) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2627249 | 0.74 | MAPT (0.69) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2559529 | 0.71 | TDP1 (0.62) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12731646 | 0.71 | MEN1 (0.60) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2649801 | 0.69 | MAPT (0.64) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2649799 | 0.69 | MAPT (0.64) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7540751 | 0.68 | SLC18A3 (0.54) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7540756 | 0.68 | SLC18A3 (0.54) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2557104 | 0.67 | NOTUM (0.65) | MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150550-B1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-02-27 | — | — | EP | disclosed |