Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL14715641 | 1.00 | MAPT (0.47) | MAPTPOLBCYP2C19CYP2C9MEN1 | |
| Carbamic Acid SCHEMBL14715674 | 0.90 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6696966 | 0.75 | MAPT (0.46) | MAPTPOLBCYP2C19CYP2C9MEN1 | |
| SCHEMBL12952781 | 0.74 | SIRT6 (0.71) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1817109 | 0.70 | SLC18A3 (0.64) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL27881 | 0.70 | MAPT (0.70) | MAPTPOLBCYP2C19CYP2C9MEN1 | |
| SCHEMBL1046692 | 0.69 | MEN1 (0.86) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3568158 | 0.69 | MAPT (0.68) | MAPTPOLBCYP2C19CYP2C9MEN1 | |
| SCHEMBL2719476 | 0.69 | MAPT (0.68) | MAPTPOLBCYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL15271381 | 0.68 | SIRT6 (0.81) | MAPTPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150550-B1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-02-27 | — | — | EP | disclosed |