Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248230 | 0.84 | PKM (0.50) | PKMKMT2AFDPSTBXAS1NAPRT | |
| SCHEMBL6248227 | 0.84 | PKM (0.50) | PKMKMT2AFDPSTBXAS1NAPRT | |
| SCHEMBL7357770 | 0.84 | PKM (0.50) | PKMKMT2AFDPSTBXAS1NAPRT | |
| Hydrochloric Acid SCHEMBL7897131 | 0.83 | TBXAS1 (0.50) | PKMKMT2AFDPSTBXAS1NAPRT | |
| SCHEMBL7384333 | 0.80 | CYP1A2 (0.62) | PKMKMT2AFDPSTBXAS1NAPRT | |
| SCHEMBL6433211 | 0.79 | CYP1A2 (0.61) | KMT2ACYP1A2RAB9A | |
| SCHEMBL2566762 | 0.77 | PKM (0.60) | PKMKMT2AFDPSTBXAS1NAPRT | |
| SCHEMBL30660224 | 0.77 | PKM (0.60) | PKMKMT2AFDPSTBXAS1NAPRT | |
| SCHEMBL12066395 | 0.77 | KMT2A (0.59) | PKMKMT2AFDPSTBXAS1NAPRT | |
| SCHEMBL2433129 | 0.76 | PKM (0.58) | PKMKMT2AFDPSTBXAS1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560974-A1 | PYRRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2013-02-27 | — | — | EP | disclosed |