Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735243 | 1.00 | POLB (0.57) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1736418 | 1.00 | POLB (0.57) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18137202 | 0.84 | KMT2A (0.54) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL701232 | 0.84 | KMT2A (0.54) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL699996 | 0.82 | MAPT (0.58) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7827059 | 0.82 | KMT2A (0.50) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4086777 | 0.82 | MAPT (0.58) | POLBMAPTMEN1KMT2AALDH1A1 | |
| Diphenylamine SCHEMBL21145177 | 0.82 | HSD17B10 (0.60) | POLBMAPTMEN1KMT2AALDH1A1 | |
| Diphenylamine SCHEMBL21145179 | 0.82 | HSD17B10 (0.60) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11050303 | 0.81 | POLB (0.59) | POLBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | claimed |
| US-12384757-B2 | Methods of synthesizing substituted pyridinone-pyridinyl compounds | ACLARIS THERAPEUTICS, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-20240043398-A1 | METHODS OF SYNTHESIZING SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | ACLARIS THERAPEUTICS, INC. | 2024-02-08 | — | — | US | disclosed |
| US-11767309-B2 | Methods of synthesizing substituted pyridinone-pyridinyl compounds | ACLARIS THERAPEUTICS, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | disclosed |
| US-20230202999-A9 | METHODS OF SYNTHESIZING SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | ACLARIS THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20220235025-A1 | METHODS OF SYNTHESIZING SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | ACLARIS THERAPEUTICS INC (US) | 2022-07-28 | — | — | US | disclosed |
| EP-2565245-B1 | Moisture-proof material | NITTO DENKO CORP (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9546303-B2 | Moisture-proof material | NITTO DENKO CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| US-20130337261-A1 | MOISTURE-PROOF MATERIAL | NITTO DENKO CORPORATION (JP) | 2013-12-19 | — | — | US | disclosed |
| EP-2666836-A2 | Moisture-proof material | Nitto Denko Corporation (JP) | 2013-11-27 | — | — | EP | disclosed |
| EP-2565245-A2 | Moisture-proof material | NITTO DENKO CORPORATION (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20130052461-A1 | MOISTURE-PROOF MATERIAL | NITTO DENKO CORPORATION (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767309-B2 | Methods of synthesizing substituted pyridinone-pyridinyl compounds | PIR, PUM1, ZRANB2 | POLB 1068/4885MAPT 3296/4885MEN1 779/4885 |
| US-12384757-B2 | Methods of synthesizing substituted pyridinone-pyridinyl compounds | PIR, PUM1, ZRANB2 | POLB 1068/4885MAPT 3296/4885MEN1 779/4885 |
| US-20220235025-A1 | METHODS OF SYNTHESIZING SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | PIR, PUM1, ZRANB2 | POLB 1068/4885MAPT 3296/4885MEN1 779/4885 |
| US-20240043398-A1 | METHODS OF SYNTHESIZING SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | PIR, PUM1, ZRANB2 | POLB 1068/4885MAPT 3296/4885MEN1 779/4885 |
| US-20230202999-A9 | METHODS OF SYNTHESIZING SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | PIR, PUM1, ZRANB2 | POLB 1068/4885MAPT 3296/4885MEN1 779/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | POLB 1887/4885MAPT 1668/4885MEN1 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.