Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699996 | 1.00 | MAPT (0.58) | MAPTTDP1ALDH1A1LMNAHTT | |
| SCHEMBL18137202 | 0.83 | KMT2A (0.54) | MAPTALDH1A1LMNAHTTPOLB | |
| SCHEMBL701232 | 0.83 | KMT2A (0.54) | MAPTALDH1A1LMNAHTTPOLB | |
| SCHEMBL14715852 | 0.82 | POLB (0.57) | MAPTALDH1A1LMNAHTTPOLB | |
| SCHEMBL1736418 | 0.82 | POLB (0.57) | MAPTALDH1A1LMNAHTTPOLB | |
| SCHEMBL1735243 | 0.82 | POLB (0.57) | MAPTALDH1A1LMNAHTTPOLB | |
| Cadaverine Tartrate SCHEMBL28055270 | 0.82 | TSHR (0.56) | MAPTTDP1ALDH1A1LMNAHTT | |
| SCHEMBL7827059 | 0.81 | KMT2A (0.50) | MAPTTDP1ALDH1A1HTTPOLB | |
| SCHEMBL701689 | 0.81 | HTT (0.58) | ALDH1A1HTTPOLBNPC1RAB9A | |
| SCHEMBL4100731 | 0.80 | PLG (0.54) | MAPTTDP1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023800-A1 | Cannabinoid receptor modulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023800-A1 | Cannabinoid receptor modulator | CNR1, CNR2, GPR18 | MAPT 4392/4885TDP1 4817/4885ALDH1A1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.