Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 3/20 | 0.43 |
| ▸ | ESRRB | O95718 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpyruvate SCHEMBL28005023 | 0.84 | CES1 (0.52) | FNTAFNTBF2CTBP2ALDH1A1 | |
| SCHEMBL5172480 | 0.83 | ESR1 (0.52) | CA2BLMESRRGESR1ESR2 | |
| SCHEMBL284962 | 0.83 | ESR1 (0.52) | CA2BLMESRRGESR1ESR2 | |
| SCHEMBL637766 | 0.83 | ESR1 (0.52) | CA2BLMESRRGESR1ESR2 | |
| 4-Hydroxyphenylpyruvic Acid SCHEMBL24157 | 0.81 | FNTA (0.72) | FNTAFNTBCA2CAMK2ABLM | |
| 4-Hydroxyphenylpyruvic Acid SCHEMBL29007535 | 0.79 | FNTA (0.76) | FNTAFNTBCA2CAMK2AF2 | |
| SCHEMBL6775096 | 0.78 | NR1H4 (0.53) | ESRRGESRRBF2ALDH1A1PLG | |
| Lactic Acid SCHEMBL28390780 | 0.73 | ESR2 (0.42) | BLMESRRGESR1ESR2ALDH1A1 | |
| 4-Hydroxyphenylpyruvic Acid SCHEMBL11057666 | 0.73 | CA2 (0.61) | FNTAFNTBCA2CAMK2AF2 | |
| SCHEMBL20943284 | 0.73 | KDM4E (0.44) | BLMALDH1A1CYP3A4PLGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052172-A1 | METHODS FOR DIAGNOSING AND TREATING CARDIAC DEFECTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-02-28 | — | — | US | disclosed |