Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | CASP6 | P55212 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vincamine SCHEMBL14095103 | 1.00 | CYP3A4 (1.00) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL3767 | 1.00 | CYP3A4 (1.00) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL30892136 | 1.00 | CYP3A4 (1.00) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL29710919 | 1.00 | CYP3A4 (1.00) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL8970683 | 1.00 | CYP3A4 (1.00) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL8134417 | 0.99 | CYP3A4 (0.98) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL6631357 | 0.98 | CYP3A4 (0.96) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL5712113 | 0.98 | CYP3A4 (0.96) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL6162410 | 0.97 | CYP3A4 (0.95) | CYP3A4KCNH2CYP2D6HIF1AMEN1 | |
| Vincamine SCHEMBL11619815 | 0.97 | CYP3A4 (0.93) | CYP3A4KCNH2CYP2D6HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6584 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739310-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) INHIBITOR COMBINATIONS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-05-13 | — | — | EP | claimed |
| US-20260035369-A1 | VINCAMINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | UNIV SOUTHWEST (CN) | 2026-02-05 | — | — | US | claimed |
| US-20250339399-A1 | SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM | BEIJING CREATRON INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) | 2025-11-06 | — | — | US | claimed |
| EP-4642484-A1 | TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE | Hangzhou Seehe Biotechnology Co., Ltd (CN) | 2025-11-05 | — | — | EP | claimed |
| EP-4642492-A1 | AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES | Hangzhou Seehe Biotechnology Co., Ltd (CN) | 2025-11-05 | — | — | EP | claimed |
| US-20250313900-A1 | COMPOSITIONS AND THERAPEUTIC AGENTS FOR MODULATING INFLAMMATORY RESPONSES ON BOTH TUMOR AND IMMUNE CELLS | THE METHODIST HOSPITAL | 2025-10-09 | — | — | US | claimed |
| US-12419860-B2 | Time release sleep aid system | NIGHTWISE, LLC (US) | 2025-09-23 | — | — | US | claimed |
| CN-116731010-B | Vincamine derivative, and preparation method and application thereof | 西南大学 | 2025-02-11 | — | — | CN | claimed |
| WO-2025007955-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) INHIBITOR COMBINATIONS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2025-01-09 | — | — | WO | claimed |
| US-20240415810-A1 | TIME RELEASE SLEEP AID SYSTEM | NIGHTWISE, LLC | 2024-12-19 | — | — | US | claimed |
| EP-0007823-A2 | 3,20-Dioxo-4,9-diene-21-hydroxy-steroid compounds, process for their preparation, their use in medicines and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-02-06 | — | — | EP | claimed |
| EP-0005100-A1 | Epoxidation reagent and its use for the epoxidation of acyclic, cyclic or polycyclic organic compounds containing at least one ethylenic unsaturation | ROUSSEL-UCLAF (FR) | 1979-10-31 | — | — | EP | claimed |
| EP-0004222-A1 | 4,5-Seco-estrane-3,5,17-trione derivatives, process for their preparation and their use for the preparation of therapeutically active compounds | ROUSSEL-UCLAF (FR) | 1979-09-19 | — | — | EP | claimed |
| US-4140777-A | Cerebral vasodilating 6-substituted vincamines | ENRICO CORVI MORA (IT) | 1979-02-20 | — | — | US | claimed |
| US-4122179-A | VASODILATORS | Mora, Enrico Corvi (IT) | 1978-10-24 | — | — | US | claimed |
| US-4021559-A | 6,7-DIHYDROXYCOUMARIN-4-METHYL-SULFONIC ACID | SYNTHELABO (FR) | 1977-05-03 | — | — | US | claimed |
| US-3979395-A | Process for the preparation of vincamine and other indole alkaloids | BUSKINE S.A. (CH) | 1976-09-07 | — | — | US | claimed |
| US-3957981-A | CEREBRAL VASODILATORS | PARCOR (FR) | 1976-05-18 | — | — | US | claimed |
| US-3957995-A | ADMINISTERING, CEREBRAL VASODILATOR ACTIVITY | PARCOR (FR) | 1976-05-18 | — | — | US | claimed |
| US-3937709-A | ENAMINES, ALKYLATION, METHYL A-BROMOMETHYL ACRYLATE, REDUCTION, OXIDATION, CYCLIZATION | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1976-02-10 | — | — | US | claimed |