Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442655 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL2201410 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL1770579 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL29819245 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL4118811 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7816978 | 0.78 | LMNA (0.56) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL11421212 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL6443612 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL10153946 | 0.77 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL19692789 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053375-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXO GROUP LIMITED | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053375-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | ABL1, MAP3K2, MAP4K2 | ALDH1A1 3050/4885SMN1; SMN2 4200/4885LMNA 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.