Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473915 | 0.91 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1471562 | 0.89 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1472223 | 0.89 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1472178 | 0.88 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL12827887 | 0.88 | FAAH (0.86) | FAAHCES1 | |
| SCHEMBL1471899 | 0.88 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1471873 | 0.88 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1471958 | 0.88 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1471276 | 0.86 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1471918 | 0.85 | FAAH (1.00) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1983994-B1 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2015-09-30 | — | — | EP | claimed |
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | claimed |
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | US | claimed |
| EP-1983994-B1 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2015-09-30 | — | — | EP | disclosed |
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | disclosed |
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | disclosed |
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | disclosed |
| EP-1983994-A2 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007098142-A2 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007098142-A2 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | US | disclosed |
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.