Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 15/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14719860 | 1.00 | FOLH1 (0.57) | FOLH1ACETDP1CYP3A4CYP2D6 | |
| SCHEMBL18145804 | 0.86 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL14729476 | 0.86 | FOLH1 (0.60) | FOLH1 | |
| SCHEMBL26264276 | 0.82 | MME (0.53) | ACETDP1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29071699 | 0.82 | NAALAD2 (0.68) | FOLH1ACETMPRSS15 | |
| SCHEMBL29071696 | 0.82 | NAALAD2 (0.68) | FOLH1ACETMPRSS15 | |
| SCHEMBL27694707 | 0.82 | NAALAD2 (0.66) | FOLH1 | |
| SCHEMBL6567538 | 0.82 | NAALAD2 (0.66) | FOLH1 | |
| SCHEMBL6567542 | 0.82 | NAALAD2 (0.66) | FOLH1 | |
| SCHEMBL4923932 | 0.81 | ALDH1A1 (0.60) | FOLH1ACEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583887-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| US-12559521-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20240425547-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2024-12-26 | — | — | US | disclosed |
| US-20240409580-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2024-12-12 | — | — | US | disclosed |
| US-12139554-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| US-12122851-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2024-10-22 | — | — | US | disclosed |
| US-20210032286-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2021-02-04 | — | — | US | disclosed |
| US-20210024574-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2021-01-28 | — | — | US | disclosed |
| US-10894807-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2021-01-19 | — | — | US | disclosed |
| US-20200377549-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2020-12-03 | — | — | US | disclosed |
| US-20180258134-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2018-09-13 | — | — | US | disclosed |
| US-10011632-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20160304555-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2016-10-20 | — | — | US | disclosed |
| WO-2013028664-A1 | PSMA IMAGING AGENTS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425547-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-10894807-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-20180258134-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-20240409580-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-12559521-B2 | PSMA imaging agents | KLK3, PSMA1, PSMA6 | FOLH1 4/4885ACE 1316/4885TDP1 3245/4885 |
| US-12139554-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-20200377549-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-12583887-B2 | PSMA imaging agents | KLK3, PSMA3, PSMA1 | FOLH1 4/4885ACE 1814/4885TDP1 3379/4885 |
| US-20210032286-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-10011632-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-12122851-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-20210024574-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
| US-20160304555-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | FOLH1 1/4885ACE 1583/4885TDP1 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.