SCHEMBL14729476

SCHEMBL14729476

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nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 17/20 0.60
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145804 1.00 FOLH1 (0.60) FOLH1LMNA
SCHEMBL29798933 0.95 FOLH1 (0.65) FOLH1LMNA
SCHEMBL14719860 0.86 FOLH1 (0.57) FOLH1
SCHEMBL14719862 0.86 FOLH1 (0.57) FOLH1
SCHEMBL18145530 0.85 ALDH1A1 (0.57)
SCHEMBL14729380 0.85 ALDH1A1 (0.57)
SCHEMBL14719940 0.84 FOLH1 (0.48) FOLH1
SCHEMBL14720022 0.84 FOLH1 (0.48) FOLH1
SCHEMBL4919361 0.83 NAALAD2 (0.61) FOLH1LMNA
SCHEMBL4919365 0.83 NAALAD2 (0.61) FOLH1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 FOLH1 4/4885LMNA 2537/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 FOLH1 4/4885LMNA 2254/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 FOLH1 1/4885LMNA 3855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.