Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.51 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658035 | 0.96 | PTPN1 (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL1025352 | 0.93 | KMT2A (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL29908078 | 0.93 | KMT2A (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL29400089 | 0.93 | KMT2A (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL30338216 | 0.93 | KMT2A (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL29354378 | 0.93 | KMT2A (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL14997839 | 0.93 | KMT2A (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL12254866 | 0.93 | KMT2A (0.58) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL24235547 | 0.92 | PTPN1 (0.57) | KMT2ACASP3PTPN1MDM4TP53 | |
| SCHEMBL29650794 | 0.91 | PTPN1 (0.60) | KMT2APTPN1MDM4TP53TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559521-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20240409580-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2024-12-12 | — | — | US | disclosed |
| US-12139554-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2024-11-12 | — | — | US | disclosed |
| US-20210024574-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2021-01-28 | — | — | US | disclosed |
| US-20180258134-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2018-09-13 | — | — | US | disclosed |
| US-10011632-B2 | PSMA imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20160304555-A1 | PSMA Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2016-10-20 | — | — | US | disclosed |
| WO-2013028664-A1 | PSMA IMAGING AGENTS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180258134-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | KMT2A 3251/4885CASP3 3170/4885PTPN1 4792/4885 |
| US-20240409580-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | KMT2A 3251/4885CASP3 3170/4885PTPN1 4792/4885 |
| US-12559521-B2 | PSMA imaging agents | KLK3, PSMA1, PSMA6 | KMT2A 2592/4885CASP3 3234/4885PTPN1 2775/4885 |
| US-12139554-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | KMT2A 3251/4885CASP3 3170/4885PTPN1 4792/4885 |
| US-10011632-B2 | PSMA imaging agents | FOLH1, KLK3, PSMA2 | KMT2A 3251/4885CASP3 3170/4885PTPN1 4792/4885 |
| US-20210024574-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | KMT2A 3251/4885CASP3 3170/4885PTPN1 4792/4885 |
| US-20160304555-A1 | PSMA Imaging Agents | FOLH1, KLK3, PSMA2 | KMT2A 3251/4885CASP3 3170/4885PTPN1 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.