SCHEMBL1025352

SCHEMBL1025352

O=C(O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.58
MDM4 O15151 2/20 0.58
TP53 P04637 2/20 0.58
TLR2 O60603 2/20 0.57
CASP3 P42574 2/20 0.55
MDM2 Q00987 5/20 0.54
PTPN1 P18031 2/20 0.52
SLC17A5 Q9NRA2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29354378 1.00 KMT2A (0.58) KMT2AMDM4TP53TLR2CASP3
SCHEMBL30338216 1.00 KMT2A (0.58) KMT2AMDM4TP53TLR2CASP3
SCHEMBL29908078 1.00 KMT2A (0.58) KMT2AMDM4TP53TLR2CASP3
SCHEMBL12254866 1.00 KMT2A (0.58) KMT2AMDM4TP53TLR2CASP3
SCHEMBL29400089 1.00 KMT2A (0.58) KMT2AMDM4TP53TLR2CASP3
SCHEMBL14997839 1.00 KMT2A (0.58) KMT2AMDM4TP53TLR2CASP3
SCHEMBL12658035 0.95 PTPN1 (0.58) KMT2AMDM4TP53TLR2CASP3
SCHEMBL14719947 0.93 KMT2A (0.57) KMT2AMDM4TP53TLR2CASP3
SCHEMBL22712859 0.93 TLR2 (0.54) KMT2AMDM4TP53TLR2CASP3
D-Glutamate SCHEMBL28574794 0.93 MDM4 (0.52) KMT2AMDM4TP53TLR2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005719-A SIRP alpha blocker polypeptide, construction method and application thereof 华东理工大学 2024-05-10 CN claimed
CN-115340472-B Glutamic acid derivative and synthesis method and application thereof 合肥工业大学 2024-05-07 CN claimed
CN-117800876-A Fmoc-O-tert-butyl-L-glutamic acid production method 浙江汉诺化工科技有限公司 2024-04-02 CN claimed
EP-3473249-A1 CROSSLINKABLE DENDRIMERS Wayne State University (US) 2019-04-24 EP claimed
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Ashvattha Therapeutics, Inc. 2017-02-02 US claimed
US-9526794-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2016-12-27 US claimed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 US claimed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 EP claimed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 WO claimed
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-03-26 US disclosed
CN-117800876-B Fmoc-O-tert-butyl-L-glutamic acid production method 浙江汉诺化工科技有限公司 2025-11-14 CN disclosed
CN-120118195-A Phage lyase analogues and uses thereof 上海多米瑞生物技术有限公司 2025-06-10 CN disclosed
US-20250041443-A1 COMPOSITIONS FOR INTRODUCING RNA INTO CELLS ETHRIS GMBH (DE) 2025-02-06 US disclosed
EP-4469468-A1 PROCESS FOR THE PREPARATION OF LINACLOTIDE Fresenius Kabi iPSUM S.r.l. (IT) 2024-12-04 EP disclosed
WO-2003014147-A1 NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME CUBIST PHARMACEUTICALS, INC. (US) 2003-02-20 WO disclosed
EP-0963999-A1 E2F ACTIVITY INHIBITORY COMPOUNDS KYOWA HAKKO KOGYO CO., LTD. (JP) 1999-12-15 EP disclosed
EP-0865283-A1 2-DEOXYSTREPTAMINE AS A MOLECULAR SCAFFOLD FOR PREPARING FUNCTIONALLY AND SPACIALLY DIVERSE MOLECULES AND PHARMACEUTICAL COMPOSITIONS THEREOF Scriptgen Pharmaceuticals Inc. (US) 1998-09-23 EP disclosed
US-5756825-A A CHELATING COMPOUND COMPRISES PROTEIN CONJUGATION FUNCTION AND A CHELATE FUNCTION; THE CHELATING COMPOUND IS 3-CARBOXYPROPYL N-(TRIS(2-((N-(BENZYLOXY)AMINO)CARBONYL)ETHYL )-METHYL)SUCCINAMATE UAB RESEARCH FOUNDATION 1998-05-26 US disclosed
WO-1997009053-A1 2-DEOXYSTREPTAMINE AS A MOLECULAR SCAFFOLD FOR PREPARING FUNCTIONALLY AND SPATIALLY DIVERSE MOLECULES AND PHARMACEUTICAL COMPOSITIONS THEREOF SCRIPTGEN PHARMACEUTICALS, INC. (US) 1997-03-13 WO disclosed
WO-1994005627-A1 HYDROXAMIC ACID-BASED BIFUNCTIONAL CHELATING COMPOUNDS UAB RESEARCH FOUNDATION (US) 1994-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170028075-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES PAM, UACA, FLT1 KMT2A 2126/4885MDM4 3299/4885TP53 2320/4885
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME CD74, HACD3, FCGR2A KMT2A 2327/4885MDM4 3919/4885TP53 1509/4885
US-20250041443-A1 COMPOSITIONS FOR INTRODUCING RNA INTO CELLS NSUN3, ABCB4, RNMT KMT2A 1671/4885MDM4 1021/4885TP53 948/4885
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES UACA, PAM, JAK3 KMT2A 2985/4885MDM4 3016/4885TP53 3102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.