Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.58 |
| ▸ | NAMPT | P43490 | 3/20 | 0.58 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035306 | 0.91 | SMYD3 (0.56) | SMYD3NAMPTCHIT1HDAC3HDAC1 | |
| SCHEMBL8255991 | 0.86 | SMYD3 (0.58) | SMYD3NAMPT | |
| SCHEMBL17888454 | 0.86 | SMYD3 (0.58) | SMYD3NAMPTMEN1KMT2A | |
| SCHEMBL5094284 | 0.85 | NAMPT (0.63) | SMYD3NAMPTHDAC3HDAC1HDAC2 | |
| SCHEMBL13325381 | 0.85 | NAMPT (0.63) | SMYD3NAMPTHDAC3HDAC1HDAC2 | |
| SCHEMBL13325386 | 0.85 | NAMPT (0.63) | SMYD3NAMPTHDAC3HDAC1HDAC2 | |
| SCHEMBL17886756 | 0.83 | SMYD3 (0.56) | SMYD3NAMPTALDH1A1LMNAMAPT | |
| SCHEMBL5630219 | 0.83 | HDAC3 (0.62) | CHIT1HDAC3HDAC1HDAC2TAAR1 | |
| SCHEMBL28801038 | 0.83 | NAMPT (0.60) | SMYD3NAMPTKDM4E | |
| SCHEMBL8257484 | 0.82 | SMN1; SMN2 (0.55) | SMYD3NAMPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |