Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032805 | 0.92 | IRAK4 (0.39) | IRAK4AAK1DGAT1FFAR1ROCK1 | |
| SCHEMBL795413 | 0.81 | IRAK4 (0.48) | IRAK4AAK1DGAT1FFAR1ROCK1 | |
| SCHEMBL29477628 | 0.81 | IRAK4 (0.48) | IRAK4AAK1DGAT1FFAR1ROCK1 | |
| SCHEMBL6125749 | 0.81 | IRAK4 (0.54) | IRAK4DGAT1KMOFFAR1ROCK1 | |
| SCHEMBL4658528 | 0.78 | AAK1 (0.36) | IRAK4AAK1DGAT1ROCK1HIF1A | |
| SCHEMBL10687 | 0.77 | KMO (0.46) | IRAK4KMOGPR119ALDH1A1 | |
| SCHEMBL14720209 | 0.76 | AAK1 (0.36) | IRAK4AAK1DGAT1ROCK1HIF1A | |
| SCHEMBL3453737 | 0.75 | DGAT1 (0.42) | IRAK4DGAT1ROCK1LIPGLPL | |
| SCHEMBL2029704 | 0.74 | AAK1 (0.37) | AAK1DGAT1ROCK1HIF1ALIPG | |
| SCHEMBL381301 | 0.74 | FFAR1 (0.46) | AAK1DGAT1FFAR1UCHL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |