Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 7/20 | 0.61 |
| ▸ | KCNJ1 | P48048 | 9/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720237 | 0.86 | FASN (0.61) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL14729648 | 0.85 | FASN (0.64) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL14842076 | 0.85 | FASN (0.65) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL14842008 | 0.85 | FASN (0.65) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL14720427 | 0.85 | FASN (0.61) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL18106920 | 0.84 | FASN (0.59) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL14720097 | 0.84 | FASN (0.60) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL14720426 | 0.84 | FASN (0.64) | FASNKCNH2CHRNA7 | |
| SCHEMBL15543586 | 0.83 | FASN (0.63) | FASNKDM1AGSK3BCHRNA7 | |
| SCHEMBL14720232 | 0.83 | FASN (0.59) | FASNKDM1AGSK3BCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744333-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-06-25 | — | — | EP | claimed |
| WO-2013028447-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | claimed |
| EP-2744333-A1 | FATTY ACID SYNTHASE INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013028447-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |