Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720669 | 1.00 | PLG (0.36) | PLGPLATLMNACYP2D6 | |
| SCHEMBL3824850 | 0.85 | PLG (0.32) | PLGPLATLMNACYP2D6 | |
| SCHEMBL14720339 | 0.76 | — | — | |
| SCHEMBL5547601 | 0.76 | CYP2D6 (0.35) | PLGPLATLMNACYP2D6 | |
| SCHEMBL3994294 | 0.76 | CYP2D6 (0.35) | PLGPLATLMNACYP2D6 | |
| SCHEMBL8084701 | 0.75 | — | — | |
| SCHEMBL4074836 | 0.68 | LMNA (0.38) | PLGPLATLMNA | |
| SCHEMBL3273457 | 0.68 | MAPT (0.44) | CYP2D6 | |
| SCHEMBL18946742 | 0.64 | — | — | |
| SCHEMBL3425719 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |