Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994294 | 1.00 | CYP2D6 (0.35) | CYP2D6MEN1TSHRKMT2APLG | |
| SCHEMBL3824850 | 0.90 | PLG (0.32) | CYP2D6PLGPLATLMNA | |
| SCHEMBL1693080 | 0.86 | MEN1 (0.33) | MEN1TSHRKMT2A | |
| SCHEMBL1692713 | 0.86 | MEN1 (0.33) | MEN1TSHRKMT2A | |
| SCHEMBL1840547 | 0.84 | MEN1 (0.32) | MEN1TSHRKMT2A | |
| SCHEMBL1843043 | 0.84 | MEN1 (0.32) | MEN1TSHRKMT2A | |
| SCHEMBL793843 | 0.79 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL794100 | 0.79 | MEN1 (0.34) | MEN1TSHRKMT2A | |
| SCHEMBL5968494 | 0.77 | TSHR (0.35) | MEN1TSHRKMT2ALMNA | |
| SCHEMBL6421985 | 0.77 | TSHR (0.35) | MEN1TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853604-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006096444-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-14 | — | — | WO | disclosed |