Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.69 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471400 | 0.90 | FAAH (0.69) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL1474087 | 0.89 | FAAH (0.69) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL1472035 | 0.88 | FAAH (0.72) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL1471366 | 0.86 | FAAH (0.71) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL1474043 | 0.84 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1471174 | 0.83 | FAAH (0.71) | FAAHCES1 | |
| SCHEMBL1472013 | 0.83 | FAAH (0.72) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL1472178 | 0.82 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1471575 | 0.82 | FAAH (0.72) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL1474042 | 0.81 | FAAH (0.69) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | claimed |