Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 20/20 | 0.69 |
| ▸ | CES1 | P23141 | 5/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474042 | 0.88 | FAAH (0.69) | FAAHCES1NCEH1 | |
| SCHEMBL1471208 | 0.87 | FAAH (0.69) | FAAHCES1NCEH1 | |
| SCHEMBL1472047 | 0.84 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1472032 | 0.84 | FAAH (0.71) | FAAHCES1 | |
| SCHEMBL1471573 | 0.82 | FAAH (1.00) | FAAHCES1 | |
| SCHEMBL1472035 | 0.82 | FAAH (0.72) | FAAHCES1 | |
| SCHEMBL1471174 | 0.81 | FAAH (0.71) | FAAHCES1 | |
| SCHEMBL1471400 | 0.81 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1474087 | 0.80 | FAAH (0.69) | FAAHCES1 | |
| SCHEMBL1472013 | 0.78 | FAAH (0.72) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | claimed |