Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721918 | 0.87 | HDAC6 (0.47) | NAMPTHRH3MCHR1 | |
| SCHEMBL14720412 | 0.82 | NAMPT (0.44) | NAMPTHRH3 | |
| SCHEMBL1787578 | 0.82 | NAMPT (0.51) | NAMPTHRH3 | |
| SCHEMBL1791888 | 0.77 | NAMPT (0.53) | NAMPTHRH3 | |
| SCHEMBL14720532 | 0.76 | HRH3 (0.36) | HRH3MCHR1 | |
| SCHEMBL14720634 | 0.76 | ALDH1A1 (0.39) | HRH3 | |
| SCHEMBL14720988 | 0.75 | SRD5A2 (0.49) | HRH3 | |
| SCHEMBL1790106 | 0.75 | HRH3 (0.50) | NAMPTHRH3 | |
| SCHEMBL14720817 | 0.75 | SRD5A2 (0.43) | HRH3 | |
| SCHEMBL14720738 | 0.74 | HRH3 (0.42) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |