Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722438 | 0.90 | HRH3 (0.39) | HRH3MCHR1SRD5A2KDM2BCHRM2 | |
| SCHEMBL14731163 | 0.86 | MCHR1 (0.38) | HRH3MCHR1SRD5A2KDM2B | |
| SCHEMBL14720591 | 0.84 | SRD5A2 (0.44) | HRH3MCHR1SRD5A2CHRM2CHRM1 | |
| SCHEMBL14720882 | 0.83 | SRD5A2 (0.43) | HRH3MCHR1SRD5A2CHRM1 | |
| SCHEMBL14720721 | 0.82 | HRH3 (0.36) | HRH3MCHR1SRD5A2 | |
| SCHEMBL14721351 | 0.81 | MCHR1 (0.40) | HRH3MCHR1SRD5A2 | |
| SCHEMBL14720831 | 0.80 | HRH3 (0.42) | HRH3MCHR1SRD5A2L3MBTL3 | |
| SCHEMBL14720897 | 0.79 | SRD5A2 (0.38) | HRH3MCHR1SRD5A2 | |
| SCHEMBL14721010 | 0.78 | SRD5A2 (0.39) | HRH3MCHR1SRD5A2CHRM1 | |
| SCHEMBL14721353 | 0.78 | SRD5A2 (0.42) | HRH3MCHR1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |