Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720476 | 0.94 | SRD5A2 (0.35) | SRD5A2HRH3MCHR1 | |
| SCHEMBL14720897 | 0.88 | SRD5A2 (0.38) | SRD5A2HRH3MCHR1 | |
| SCHEMBL14721353 | 0.87 | SRD5A2 (0.42) | SRD5A2HRH3MCHR1 | |
| SCHEMBL14720831 | 0.81 | HRH3 (0.42) | SRD5A2HRH3MCHR1 | |
| SCHEMBL14722982 | 0.81 | SRD5A2 (0.38) | SRD5A2HRH3 | |
| SCHEMBL14720532 | 0.79 | HRH3 (0.36) | SRD5A2HRH3MCHR1 | |
| SCHEMBL14720475 | 0.76 | SRD5A2 (0.39) | SRD5A2HRH3 | |
| SCHEMBL14720591 | 0.73 | SRD5A2 (0.44) | SRD5A2HRH3MCHR1 | |
| SCHEMBL14720522 | 0.73 | HRH3 (0.39) | SRD5A2HRH3MCHR1 | |
| SCHEMBL14721067 | 0.72 | SRD5A2 (0.42) | SRD5A2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |