Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 6/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723376 | 0.84 | MEN1 (0.42) | MEN1KMT2ASRD5A2ALDH1A1CCR1 | |
| SCHEMBL14721332 | 0.83 | HRH3 (0.39) | OPRM1MEN1KMT2ASRD5A2CCR1 | |
| SCHEMBL14721633 | 0.82 | HRH3 (0.36) | OPRM1OPRK1MEN1KMT2ACCR1 | |
| SCHEMBL14720774 | 0.82 | HRH3 (0.40) | OPRM1MEN1KMT2ASRD5A2CCR1 | |
| SCHEMBL14731164 | 0.82 | SRD5A2 (0.34) | OPRM1OPRD1OPRK1SRD5A2ALOX15 | |
| SCHEMBL14720493 | 0.81 | MEN1 (0.35) | MEN1KMT2ASRD5A2CCR1 | |
| SCHEMBL14721195 | 0.81 | MEN1 (0.40) | MEN1KMT2ASRD5A2ALDH1A1CCR1 | |
| SCHEMBL14720519 | 0.81 | HRH3 (0.34) | CCR1 | |
| SCHEMBL14731091 | 0.79 | OPRM1 (0.35) | OPRM1MEN1KMT2ASRD5A2CCR1 | |
| SCHEMBL14720746 | 0.79 | HRH3 (0.38) | MEN1KMT2ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |