Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 10/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721195 | 0.97 | MEN1 (0.40) | MEN1KMT2AHRH3CCR1SRD5A2 | |
| SCHEMBL14721332 | 0.86 | HRH3 (0.39) | MEN1KMT2AHRH3CCR1SRD5A2 | |
| SCHEMBL14721633 | 0.85 | HRH3 (0.36) | MEN1KMT2AHRH3CCR1 | |
| SCHEMBL14720774 | 0.85 | HRH3 (0.40) | MEN1KMT2AHRH3CCR1SRD5A2 | |
| SCHEMBL14720563 | 0.84 | OPRM1 (0.36) | MEN1KMT2ACCR1SRD5A2ALDH1A1 | |
| SCHEMBL14720796 | 0.84 | SRD5A2 (0.39) | MEN1KMT2AHRH3SRD5A2ALDH1A1 | |
| SCHEMBL14720732 | 0.83 | CYP2C19 (0.41) | MEN1KMT2AHRH3SRD5A2ALDH1A1 | |
| SCHEMBL14720493 | 0.82 | MEN1 (0.35) | MEN1KMT2ACCR1SRD5A2 | |
| SCHEMBL14720746 | 0.81 | HRH3 (0.38) | MEN1KMT2AHRH3CCR1 | |
| SCHEMBL14720519 | 0.81 | HRH3 (0.34) | HRH3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |