Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL4667948 | 0.89 | — | — | |
| Alcohol SCHEMBL1445684 | 0.89 | ALDH1A1 (0.43) | — | |
| Alcohol SCHEMBL29060510 | 0.86 | ALDH1A1 (0.40) | — | |
| Butane SCHEMBL9423505 | 0.76 | — | — | |
| Alcohol SCHEMBL2464657 | 0.74 | TSHR (1.00) | — | |
| Alcohol SCHEMBL17770701 | 0.74 | — | — | |
| Alcohol SCHEMBL29975647 | 0.74 | — | — | |
| Alcohol SCHEMBL54946 | 0.74 | — | — | |
| Alcohol SCHEMBL9461084 | 0.74 | TSHR (1.00) | — | |
| Alcohol SCHEMBL6910520 | 0.74 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456206-A | Alpha-fluoroalkyl substituted cyclopropenyl ether (alcohol), preparation method and application thereof | 武汉大学 | 2022-05-10 | — | — | CN | claimed |
| US-11198898-B2 | Chemical tools for imaging phospholipase D activity | CORNELL UNIVERSITY (US) | 2021-12-14 | — | — | US | claimed |
| US-20190085373-A1 | CHEMICAL TOOLS FOR IMAGING PHOSPHOLIPASE D ACTIVITY | CORNELL UNIVERSITY | 2019-03-21 | — | — | US | claimed |
| CN-114456206-A | Alpha-fluoroalkyl substituted cyclopropenyl ether (alcohol), preparation method and application thereof | 武汉大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-106164263-B | Cyclopropene amino acids and methods | 英国研究与创新署 | 2022-02-11 | — | — | CN | disclosed |
| US-11198898-B2 | Chemical tools for imaging phospholipase D activity | CORNELL UNIVERSITY (US) | 2021-12-14 | — | — | US | disclosed |
| US-20190085373-A1 | CHEMICAL TOOLS FOR IMAGING PHOSPHOLIPASE D ACTIVITY | CORNELL UNIVERSITY | 2019-03-21 | — | — | US | disclosed |
| US-10160836-B2 | Water dispersible hyperbranched polymer composition | NIPSEA TECHNOLOGIES PTE LTD (SG) | 2018-12-25 | — | — | US | disclosed |
| US-20170166705-A1 | Water Dispersible Hyperbranched Polymer Composition | NIPSEA TECHNOLOGIES PTE LTD (SG) | 2017-06-15 | — | — | US | disclosed |
| US-9533957-B2 | Tetrazines and method of synthezising the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-03 | — | — | US | disclosed |
| WO-2016068793-A1 | WATER DISPERSIBLE HYPERBRANCHED POLYMER COMPOSITION | NIPSEA TECHNOLOGIES PTE LTD (SG) | 2016-05-06 | — | — | WO | disclosed |
| US-9284470-B2 | Aqueous dispersible polymer composition | NIPSEA TECHNOLOGIES PTE LTD (SG) | 2016-03-15 | — | — | US | disclosed |
| US-20150099277-A1 | NOVEL TETRAZINES AND METHOD OF SYNTHEZISING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-04-09 | — | — | US | disclosed |
| US-20140316044-A1 | AQUEOUS DISPERSIBLE POLYMER COMPOSITION | NIPSEA TECHNOLOGIES PTE LTD (SG) | 2014-10-23 | — | — | US | disclosed |
| EP-2748262-A1 | AN AQUEOUS DISPERSIBLE POLYMER COMPOSITION | Nipsea Technologies Pte Ltd. (SG) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013152359-A1 | NOVEL TETRAZINES AND METHOD OF SYNTHESIZING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013028134-A1 | AN AQUEOUS DISPERSIBLE POLYMER COMPOSITION | NIPSEA TECHNOLOGIES PTE LTD (SG) | 2013-02-28 | — | — | WO | disclosed |